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Click Chemistry Tools的生物素疊氮Biotin Azide

更新時(shí)間:2023-10-16   點(diǎn)擊次數(shù):1423次

Biotin Azide/生物素疊氮

生物素疊氮中文介紹:

生物素疊氮化物(PEG4羧酰胺-6-疊氮己基生物素)是不可裂解的疊氮化生物素化試劑,通過(guò)銅催化的點(diǎn)擊反應(yīng)與末端炔烴反應(yīng),產(chǎn)生穩(wěn)定的三唑鍵。它還通過(guò)無(wú)銅的“點(diǎn)擊化學(xué)"反應(yīng)與環(huán)辛炔反應(yīng),形成穩(wěn)定的三唑,不需要銅催化劑或高溫。生物素疊氮化物允許用生物素選擇性標(biāo)記各種炔化分子(如DNA、寡核苷酸和蛋白質(zhì)),以便隨后使用鏈霉親和素、親和素或中性親和素生物素結(jié)合蛋白進(jìn)行檢測(cè)或親和®純化。


Biotin Azide英文介紹:

Biotin Azide (PEG4 carboxamide-6-Azidohexanyl Biotin) is non-cleavable, azide-activated biotinylation reagent that reacts with terminal alkynes via a copper-catalyzed click reaction to produce a stable triazole linkage. It also reacts with cyclooctynes via a copper-free “click chemistry" reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. Biotin Azide allows for selective labeling of various alkynylated molecules (such as DNA, oligonucleotides, and proteins) with biotin for the subsequent detection or affinity purification with streptavidin, avidin or NeutrAvidin® biotin-binding protein.


Biotin Azide結(jié)構(gòu):

image.png


生物素疊氮結(jié)構(gòu):

1a8df0b66b6d2cb6e96ef803ff6402ae_1265_Structure.png


產(chǎn)品訂購(gòu)信息:

image.png


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